MemoCard lernen mit System

ADENOSINE (Adenocard) MOA

slows conduction AV node, interrupt re-entrant pathway neg. chronotrope acts onSA cells, 1st choice PSVT

TRANEXAMIC ACID (TXA, Cyklokapron) MOA

Reduces plasminogen activation, mitigating conversion to plasmin.

PROMETHAZINE (Phenergan) MOA

H receptor antagonist that blocks the actions of histamines by competitive antagonism at the H receptor. In addition to antihistamine effects, promethazine also possesses sedative, anti-motion, antiemetic, and considerable anticholinergic activity.

DILTIAZEM HCL (Cardizem) MOA

Block influx of calcium ions into cardiac muscle. Arterial and venous vasodilator. Reduces preload and afterload. Reduces myocardial oxygen demand.

METOPROLOL (Lopressor) MOA

Selective inhibitor of beta1-adrenergic receptors; completely blocks beta1 receptors, with little or no effect on beta 2 receptors at doses <100 mg;

ASPIRIN MOA

Prostaglandin inhibition Blocks Thromboxane A2 via COX 1. Vaso-Dil via the COX 2 pathway.

SUCCINYLCHOLINE (Anectine) MOA

Ultra short acting depolarizing skeletal relaxant that mimics acetylcholine as it binds with the cholinergic receptors on the motor end plate, producing a phase I block as manifested by fasciculations.

DIPHENHYDRAMINE (Benadryl) MOA

Blocks H receptors; decreases vasodilatation Reverses extrapyramidal reactions.

MANNITOL 20% MOA

Promotes the movement of fluid form the intracellular space to the extracellular space. Decreases cerebral edema and intracranial pressure. Promotes urinary excretion of toxins.

NITROPASTE MOA

Smooth muscle relaxant acting on vascular, bronchial, uterine and intestinal smooth muscle. Dilation of arterioles and veins in the periphery reduces preload and afterload, decreases the workload of the heart and, thereby, myocardial oxygen demand.

GLUCAGON beta blcker OD MOA

stabilize cardiac rhythm in beta-blocker overdose.

THIAMINE (Vitamin B1) MOA

Combines with ATP to form thiamine pyrophosphate coenzyme, a necessary component for carbohydrate metabolism. The brain is extremely sensitive to thiamine deficiency.

LORAZEPAM (Ativan) MOA

Anxiolytic, anticonvulsant, sedative; suppresses seizure produced by foci in cortex, thalamus and limbic areas.

HYDROCORTISONE/METHYLPREDNISOLONE (Solu-Cortef, Solu-Medrol) MOA

Suppresses acute and chronic inflammation Replaces absent glucocorticoids Immunosuppressive

NITROGLYCERIN MOA

Smooth muscle relaxant with dilation of arterioles and veins in the periphery, reduces preload and afterload, decreases the workload of the heart and, thereby, myocardial oxygen demand.

EPINEPHRINE allergic MOA

bronchial smooth muscle relaxation and dilation of skeletal vasculature Blocks histamine release.

IPRATROPIUM BROMIDE (Atrovent) MOA

Blocks acetylcholine at the parasympathetic sites in bronchial smooth muscle causing bronchodilation.

DOPAMINE (Inotropin) Andregic MOA

alpha 1 effects

PROCAINAMIDE (Pronestyl) MOA

Suppresses phase IV depolarization in normal ventricular muscle and Purkinje fibers, reducing automaticity of ectopic pacemakers; suppresses reentry dysrhythmias by slowing intraventricular conduction.

ATROPINE SULFATE MOA

inhibits action of acetylcholine at postganglionic parasympathetic neuroeffector sites.

ROCURONIUM (Zemuron) MOA

Rocuronium produces complete muscular relaxation by binding to the receptor for acetylcholine at the neuromuscular junction, without initiating depolarization of the muscle membrane. As the concentration of acetylcholine rises in the neuromuscular junction, Pancuronium is displaced and muscle tone is regained.

LIDOCAINE HCL (2%) MOA

Decreases automaticity by slowing the rate of Phase 4 depolarization.

HALOPERIDOL (Haldol) MOA

strong antidopaminergic and weak anticholinergic. Acts on the CNS to depress subcortical areas, midbrain, and ascending reticular activating system in the brain.

KETOROLAC (Toradol) MOA

anti-inflammatory acting non-narcotic analgesic activity by inhibiting prostaglandin synthesis.

PANCURONIUM (Pavulon) MOA

Pancuronium produces complete muscular relaxation by binding to the receptor for acetylcholine at the neuromuscular junction, without initiating depolarization of the muscle membrane. As the concentration of acetylcholine rises in the neuromuscular junction, Pancuronium is displaced and muscle tone is regained.

HEPARIN SODIUM MOA

IX, XI, XII, plasmin. Does not lyse existing clots.

TETRACAINE MOA

Blocks the initiation and conduction of nerve impulses

VERAPAMIL (Isoptin) MOA

Verapamil inhibits the movement of calcium ions across cell membranes. The slow calcium ion current blocked by verapamil is more important for the activity of the sinoatrial node and atrioventricular node than for many other tissues in the heart. Verapamil decreases atrial automaticity, reduces atrioventricular conduction velocity, and prolongs the atrioventricular nodal refractory period. In addition, verapamil depresses myocardial contractility, reduces vascular smooth muscle tone, and dilates coronary arteries and arterioles in normal and ischemic tissues.

RACEMIC EPINEPHRINE MOA

Stimulates alpha-1 receptors reducing subglottic edema in croup by mucosal vascular bed vasoconstriction. Stimulates beta-2 receptors in the smaller airways in lungs causing bronchodilation with relaxation of bronchial smooth muscles. Reduces airway resistance. Useful in treating laryngeal edema; inhibits histamine release.

MORPHINE SULFATE MOA

Alleviates pain through CNS actions Suppresses fear and anxiety centers in brain. Depresses brain stem respiratory centers. Decreases preload and afterload, decreasing myocardial oxygen demand.

AMIODARONE (Cordarone) MOA

Class III K channel blocker. Prolongation of Action Potential; non-competitive A and B sympathetic blocker; Ca,Na channel blocking effects.

SODIUM BICARBONATE 8.4% MOA

Reacts with hydrogen ions to form water and carbon dioxide

HYDROXOCOBALAMIN (Vitamin B 12) MOA

hydroxocobalamin binds cyanide ions to form cyanocobalamin

DIAZEPAM (Valium) seizure MOA

Potentates inhibitory neurotransmitters. Raises seizure threshold.Induces amnesia and sedation.

ALBUTEROL (Proventil, Ventolin) MOA

Selective b-2 agonist stimulates adrenergic receptors/smooth muscle relaxation, bronchdilator, peripheral vasodialtion.

OXYGEN MOA

Reverses hypoxemia.

FUROSEMIDE (Lasix) MOA

Inhibits electrolyte reabsorption promotes excretion of sodium, potassium, chloride

NOREPINEPHRINE (Levophed) MOA

Potent alpha-agonist resulting in intense peripheral vasoconstriction, positive chronotropic and increased inotropic effect with increased cardiac output. Alpha adrenergic activity resulting in peripheral vasoconstriction and beta-adrenergic activity leading to inotropic stimulation of the heart and coronary artery vasodilation.

AMYL NITRITE, SODIUM NITRITE, SODIUM THIOSULFATE (Cyanide Antidote Kit) MOA

produces thiocyanate, which is then excreted

ACETAMINOPHEN (Tylenol, Ofrimev) MOA

analgesics and antipyretics.

ACTIVATED CHARCOAL MOA

Adsorbs toxic GI

NALOXONE (Narcan) MOA

Competitive inhibition at narcotic receptor sites. Reverse respiratory depression secondary to depressant drugs. Completely inhibits the effect of morphine.

GLUCAGON hyperglcemia MOA

Increases blood glucose by stimulating glycolysis.

ONDANSETRON (Zofran) MOA

Selective 5-HT receptor antagonist, blocking serotonin, both peripherally on vagal nerve terminals and centrally in the CNS chemoreceptor trigger zone

DEXTROSE MOA

Rapidly increases serum glucose l

CALCIUM CHLORIDE / CALCIUM GLUCONATE MOA

inotrope May enhance vent automaticity. Helps stabilize the cell membrane

ETOMIDATE (Amidate) MOA

Short acting hypnotic of the reticular activating system

MEPERIDINE (Demerol) MOA

Synthetic opioid agonist that acts on opioid receptors to produce analgesia, euphoria, respiratory and physical depression; a schedule II drug with potential for physical dependency and abuse.

FENTANYL CITRATE (Sublimaze) MOA

narcotic analgesic

KETAMINE (Ketalar) RSI MOA

Blocks pain receptors and minimizes spinal cord activity, between the thalamus and the limbic system.

EPINEPHRINE cardiac MOA

+chrono, +inno,+dromo + automaticity.

KETAMINE (Ketalar) delerium MOA

Blocks pain receptors and minimizes spinal cord activity, between the thalamus and the limbic system.

DOPAMINE (Inotropin) dopaminergic MOA

dilate renal and splanchnic vasculature at low doses.

VASOPRESSIN (Pitressin) MOA

Vasopressin acts by direct stimulation of smooth muscle receptors. When given in extremely high doses, it acts as a noradrenergic peripheral vasoconstrictor.

DIAZEPAM (Valium)cardio MOA

Potentates inhibitory neurotransmitters. Raises seizure threshold.Induces amnesia and sedation.

HYDROMORPHONE (Dilaudid) MOA

synthetic analog morphine

FLUMAZENIL (Romazicon) MOA

Flumazenil antagonizes benzodiazepines in CNS. reverse sedation, impairment of recall, and psychomotor impairment produced by benzodiazepines. Will not reverse hypoventilation or antagonize CNS effects of ethanol, barbiturates, or opioids.

VECURONIUM (Norcuron) MOA

Vecuronium is an intermediate-acting, non-depolarizing, neuromuscular blocking agent. Non-depolarizing agents produce skeletal muscle paralysis by blockade at the myoneural junction. Unlike depolarizing agents, vecuronium has little agonist activity, with no depolarizing effect at the motor endplate.

GLUCOSE -ORAL MOA

fast glucose

PRALIDOXIME CHLORIDE (2-PAM, Protopam) MOA

Reactivation of cholinesterase to effectively act as an antidote to organophosphate pesticide poisoning. This action allows for destruction of accumulated acetylcholine at the neuromuscular junction.

DEXAMETHASONE (Decadron) MOA

surpress inflammation, immunosuppressive

DOPAMINE (Inotropin) Beta-andregenic MOA

+ inotropy. +chronotropy.

MIDAZOLAM (Versed) MOA

Increased production of GABA, an inhibitory neurotransmitter, causing procedural amnesia; anesthesia; skeletal muscle relaxation. Anxiolytic and sedative / hypnotic properties similar to other benzodiazepines.

KETAMINE (Ketalar) pain MOA

Blocks pain receptors and minimizes spinal cord activity, between the thalamus and the limbic system.

MAGNESIUM SULFATE MOA

Reduces striated muscle contractions and blocks peripheral neuromuscular transmission by reducing acetylcholinesterase release at the myoneural junction; manages seizures in toxemia of pregnancy; induces uterine relaxation; can cause bronchodilation after beta agonists and anticholinergics have been used.

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P125moa